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FLASH GENE
Symbol INTU contributors: mct - updated : 25-08-2017
HGNC name inturned planar cell polarity effector homolog (Drosophila)
HGNC id 29239
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • PDZ domain
  • HOMOLOGY
    Homologene
    FAMILY
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule
    intracellular,cytoplasm,cytoskeleton,intermed filament
    basic FUNCTION
  • protein binding activity
  • planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia
  • is required for ciliogenesis
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein binding
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS