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FLASH GENE

Symbol

FMO3

contributors: mct - updated : 24-01-2009

HGNC name	flavin containing monooxygenase 3
HGNC id	3771

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

FMO family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm,organelle,membrane
	intracellular,cytoplasm,organelle,endoplasmic reticulum
	intracellular,cytoplasm,cytosolic,microsome

basic FUNCTION	converts fishy-smelling trimethylamine (TMA) into odorless trimethylamine-N-oxide (TMAO) (Teresa 2006)
	involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule	cofactor,
	FAD

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

TMA

Susceptibility

to trimethylaminuria

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS