Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | FMO3 | contributors: mct - updated : 24-01-2009 |
HGNC name | flavin containing monooxygenase 3 |
HGNC id | 3771 |
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Corresponding disease |
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Location | 1q24.3 Physical location : 171.060.017 - 171.086.957 | ||
Synonym symbol(s) | FMOII, MGC34400 | ||
EC.number | 1.14.13.8 |
DNA |
TYPE | like-sequence |
SPECIAL FEATURE | arranged in tandem, component of a cluster |
STRUCTURE | 26.92 kb 9 Exon(s) |
Genomic sequence alignment details |
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10 Kb 5' upstream gene genomic sequence study |
regulatory sequence | Promoter (CAAT box) |
cytosine-phosphate-guanine/HTF | |
Binding site | |
text structure | NFY, USF1, an unidentified GC box binding protein, and YY1 appear to play major roles regulating constitutive FMO3 transcription (Klick 2007) |
MAPPING | cloned | Y | linked | N | status | confirmed |
Map | cen - D1S210 - D1S1715 - FMO3 - D1S1542 - D1S815 - qter |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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tissue |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
Homologene |
FAMILY | FMO family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,membrane | |
intracellular,cytoplasm,organelle,endoplasmic reticulum | |
intracellular,cytoplasm,cytosolic,microsome |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, |
FAD |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | TMA |
Susceptibility | to trimethylaminuria |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |