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FLASH GENE
Symbol USP3 contributors: mct/npt - updated : 16-03-2010
HGNC name ubiquitin specific peptidase 3
HGNC id 12626
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • deubiquitin family
  • peptidase C19 family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • ubiquitin specific protease
  • cleaving a ubiquitin-proline bond
  • only the second known ubiquitin-specific protease capable of efficiently cleaving a ubiquitin-proline bond (Sloper-Mould 1999)
  • implicated as a novel chromatin modifier in the maintenance of genome integrity (Nicassio 2007)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS