basic FUNCTION
| performing post-translational protein translocation into the ER (Sec61-Sec62-Sec63 complex) |
|
performing the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway (Sec61-Sec62-Sec63 complex) |
|
acting as an endoplasmic reticulum receptor |
|
key component of the protein translocation machinery in the mammalian endoplasmic reticulum (ER), and involved in the post-translation processing of secretory proteins |
|
possible role for SEC63 in decidualization |
|
PRKCSH and SEC63 function in protein translocation and quality control pathways in the endoplasmic reticulum |