basic FUNCTION
| modulating processing of the beta-APP and hence formation of beta-APP |
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stimulates MMP24 activity when expressed at low levels in an EWV-dependent fashion, but inhibits its activity at higher levels independent of the EWV motif |
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potentially functions in the nucleus by a mechanism distinct from conventional transactivators |
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adaptor scaffolding protein involved in formation of multiprotein complexes, and trafficking and metabolism of membrane proteins such as the beta-amyloid precursor protein |
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may be the adaptor proteins that regulate the trafficking of MMP24 |
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regulates FURIN distribution mainly through interaction with the acidic peptide signal of Furin |
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regulates the HIF1AN-HIF1A pathway, which controls ATP production in macrophages |
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