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FLASH GENE
Symbol BCYRN1 contributors: mct - updated : 29-06-2007
HGNC name brain cytoplasmic RNA 1, Bc1 analog (mouse)
HGNC id 1022
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a 5-prime domain derived from Alu elements that contains consensus elements A and B of the split RNA polymerase III promoter and signal recognition particle motifs
  • a central A-rich region, central domain with a single-stranded homopolymeric A segment of 22 nucleotides
  • a unique 3-prime sequence containing 42 nucleotides
    • HOMOLOGY
    interspecies ortholog to murine Bc1
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION
    text
  • neuropil areas of the retina
  • localizes to synaptodendritic domains
    • basic FUNCTION
  • micro RNA regulating dentritic protein synthesis
  • determine the specificity of FMR1 function by linking the regulated mRNAs and FMR1
  • translational repressor that have been implicated in the modulation of postsynaptic protein repertoires in neurons, as FMR1 (but BCYRN1 and FMR1 operate at different levels in the translation pathway)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of a ribonucleoprotein complex
    INTERACTION
    DNA
    RNA
    small molecule
    protein potential analog of Bc1, associated with FMR1 for regulating the translation of specific mRNA at synapses
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS