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FLASH GENE
Symbol BCYRN1 contributors: mct - updated : 29-06-2007
HGNC name brain cytoplasmic RNA 1, Bc1 analog (mouse)
HGNC id 1022
Location 2p21-p16      Physical location : 70.430.034 - 70.948.962
Synonym symbol(s) BC200RNA, BC200alpha, BC1
DNA
TYPE functioning gene
STRUCTURE 0.00 kb     1 Exon(s)    1 Copie(s)
regulatory sequence
MAPPING cloned Y linked Y status provisional
Map pter - D2S177 - D2S119 - D2S1736 - BCYRN1 - D2S357 - cen
Authors Basile (98)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbraindiencephalonhypothalamus  
 brainforebraincerebral cortex  
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsensoryvisual  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a 5-prime domain derived from Alu elements that contains consensus elements A and B of the split RNA polymerase III promoter and signal recognition particle motifs
  • a central A-rich region, central domain with a single-stranded homopolymeric A segment of 22 nucleotides
  • a unique 3-prime sequence containing 42 nucleotides
  • HOMOLOGY
    interspecies ortholog to murine Bc1
    Homologene
    FAMILY
    CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION
    text
  • neuropil areas of the retina
  • localizes to synaptodendritic domains
  • basic FUNCTION
  • micro RNA regulating dentritic protein synthesis
  • determine the specificity of FMR1 function by linking the regulated mRNAs and FMR1
  • translational repressor that have been implicated in the modulation of postsynaptic protein repertoires in neurons, as FMR1 (but BCYRN1 and FMR1 operate at different levels in the translation pathway)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component component of a ribonucleoprotein complex
    INTERACTION
    DNA
    RNA
    small molecule
    protein potential analog of Bc1, associated with FMR1 for regulating the translation of specific mRNA at synapses
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS