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FLASH GENE
Symbol EIF3I contributors: - updated : 17-08-2007
HGNC name eukaryotic translation initiation factor 3, subunit I
HGNC id 3272
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • five WD-40 repeats
  • a putative ATP/GTP binding site
    • HOMOLOGY
    Homologene
    FAMILY eukaryotic translation initiation factor family
    CATEGORY RNA associated , tumor suppressor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytosolic,ribosome
    basic FUNCTION
  • stabilizing initiator Met tRNA (TRIMs) binding to 40S subunits
  • promoting the association of Met-tRNA and mRNA
  • cadmium-responsive proto-oncogene
    • CELLULAR PROCESS protein, translation/synthesis
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • components of the EIF3 multiprotein complex, 600kDa
    • INTERACTION
    DNA
    RNA binding to the 40S ribosome
    small molecule
    protein
  • binding to TGFBR
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS