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FLASH GENE
Symbol RHAG contributors: - updated : 07-01-2005
HGNC name Rhesus blood group-associated glycoprotein
HGNC id 10006
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
twelve transmembrane domains (12TM)
conjugated GlycoP
HOMOLOGY
interspecies homolog to murine Rhag
intraspecies homolog to RH (30kD components (see RH)),highly
Homologene
FAMILY RH family
CATEGORY structural protein , antigen
SUBCELLULAR LOCALIZATION     plasma membrane
text integral membrane protein
basic FUNCTION
  • strictly required for the transport of antigen to cell surface of red blood cells
  • facilitating NH3 movement across the red blood cells membrane
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text mediating uptake of ammonium across cell membranes
    PATHWAY
    metabolism
    signaling
    a component component of the RH antigen multisubunit complex,required for transport and assembly of the Rh membrane complex to the red blood cell surface
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) RHNR
    related resource Blood Group Antigen Mutation Database
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS