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FLASH GENE
Symbol RHAG contributors: - updated : 07-01-2005
HGNC name Rhesus blood group-associated glycoprotein
HGNC id 10006
DNA
TYPE functioning gene
STRUCTURE 31.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
motif repetitive sequence   ALU   long interspersed repetitive elements
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
cells
SystemCellPubmedSpeciesStageRna symbol
Blood/Hematopoieticerythrocyte
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
twelve transmembrane domains (12TM)
conjugated GlycoP
HOMOLOGY
interspecies homolog to murine Rhag
intraspecies homolog to RH (30kD components (see RH)),highly
Homologene
FAMILY RH family
CATEGORY structural protein , antigen
SUBCELLULAR LOCALIZATION     plasma membrane
text integral membrane protein
basic FUNCTION
  • strictly required for the transport of antigen to cell surface of red blood cells
  • facilitating NH3 movement across the red blood cells membrane
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    text mediating uptake of ammonium across cell membranes
    PATHWAY
    metabolism
    signaling
    a component component of the RH antigen multisubunit complex,required for transport and assembly of the Rh membrane complex to the red blood cell surface
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) RHNR
    related resource Blood Group Antigen Mutation Database
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS