basic FUNCTION
| dehydrogenase/reductase activity |
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reduced fatty acids to fatty alcohols  |
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involved in the metabolism of a large variety of compounds, including steroid hormones, prostaglandins, retinoids, lipids and xenobiotics  |
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FAR1 activity is elevated in plasmalogen-deficient cells, and conversely, the levels of this enzyme are restored to normal upon plasmalogen supplementation  |
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essential for supplying fatty alcohols required for ether bond formation in ether glycerophospholipid synthesis  |
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peroxisomal tail-anchored protein  |
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is a rate-limiting enzyme for plasmalogen synthesis |
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reduces fatty acids to their respective fatty alcohols for the plasmalogen-biosynthesis pathway  |