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FLASH GENE
Symbol SLC25A45 contributors: mct - updated : 06-11-2020
HGNC name solute carrier family 25, member 45
HGNC id 27442
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY transport carrier
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm,organelle,mitochondria,inner
intracellular,cytoplasm,organelle,membrane
basic FUNCTION
  • SLC25A45 is a transport protein in the mitochondrial membrane, containing active thyroid-responsive elements
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to mucinous histological subtype of epithelial ovarian cancer
    Variant & Polymorphism
  • SNP of SLC25A45 was associated with the mucinous histological subtype of epithelial ovarian cancer
    • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS