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FLASH GENE
Symbol SLC25A45 contributors: mct - updated : 06-11-2020
HGNC name solute carrier family 25, member 45
HGNC id 27442
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestine   highly
Lymphoid/Immunespleen   highly
Nervousbrainforebraincerebral cortex highly
 nervecranial nerve  highly
Olfactory (smell)olfactory bulb   highly
Reproductivefemale systemuteruscervix highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY transport carrier
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm,organelle,mitochondria,inner
intracellular,cytoplasm,organelle,membrane
basic FUNCTION
  • SLC25A45 is a transport protein in the mitochondrial membrane, containing active thyroid-responsive elements
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to mucinous histological subtype of epithelial ovarian cancer
    Variant & Polymorphism
  • SNP of SLC25A45 was associated with the mucinous histological subtype of epithelial ovarian cancer
    • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS