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FLASH GENE
Symbol SLC1A4 contributors: KTN - updated : 13-12-2007
HGNC name solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
HGNC id 10942
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • ten transmembrane spanning segments (10TM)
    • conjugated GlycoP , PhosphoP
    HOMOLOGY
    interspecies homolog to dog SLC1A4 (93.2 pc)
    homolog to chimpanzee SLC1A4 (100 pc)
    homolog to rattus Slc1a4 (88.1 pc)
    homolog to murine Slc1a4 (89.9 pc)
    Homologene
    FAMILY
  • solute carrier family 1, glutamate/neutral amino acid
  • sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • melanosome
    • basic FUNCTION
  • acting as a transporter for alanine, serine, cysteine, and threonine
  • exhibiting sodium dependence
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS