Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol SLC1A4 contributors: KTN - updated : 13-12-2007
HGNC name solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
HGNC id 10942
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 4562 55 532 - -
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivemouthtongue  moderately
Endocrineadrenal gland   highly
 pancreas    
Lymphoid/Immunethymus   moderately
Nervousbrain   moderately
Reproductivefemale systemuteruscervix moderately
 female systembreastmammary gland moderately
Respiratoryrespiratory tracttrachea  moderately
Skin/Tegumentskin   moderately
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone  moderately
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Muscular    
cell lineage
cell lines
fluid/secretion moderately in blood and predominantly in lymph
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • ten transmembrane spanning segments (10TM)
  • conjugated GlycoP , PhosphoP
    HOMOLOGY
    interspecies homolog to dog SLC1A4 (93.2 pc)
    homolog to chimpanzee SLC1A4 (100 pc)
    homolog to rattus Slc1a4 (88.1 pc)
    homolog to murine Slc1a4 (89.9 pc)
    Homologene
    FAMILY
  • solute carrier family 1, glutamate/neutral amino acid
  • sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family
  • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    text
  • melanosome
  • basic FUNCTION
  • acting as a transporter for alanine, serine, cysteine, and threonine
  • exhibiting sodium dependence
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS