basic FUNCTION
| functions as a deubiquitinating enzyme |
|
modulation of USP4 expression may provide a new means to interfere with canonical Wnt signalling in a variety of physiological and pathological conditions |
|
having a role in spliceosome regulation |
|
serves as a critical control to downregulate TNF-induced NFKB activation through deubiquitinating MAP3K7 |
|
deubiquitinase targeting TRAF2 and TRAF6 for deubiquitination |
|
negative regulator of TNF- and IL1B-induced cancer cell migration |
|
USP4 and USP15 extend the life of activated receptors against the negative pressure of receptor-ubiquitinating complexes, but through distinct modes of action |