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FLASH GENE
Symbol GPR180 contributors: np - updated : 13-12-2005
HGNC name G protein-coupled receptor 180
HGNC id 28899
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a motif common to the Rhodopsin-like GPCR (G-protein-coupled receptor) superfamily
    • conjugated GlycoP
    HOMOLOGY
    interspecies ortholog to chimpanzee LOC467300
    ortholog to rattus MGC94555
    Homologene
    FAMILY
  • G protein-coupled receptor superfamily
    • CATEGORY regulatory , receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • might playing an important role in the regulation of vascular remodeling
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    induced by up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
  • a good target for development of drugs in the prevention of vascular restenosis
    • Marker
    Therapy target
    ANIMAL & CELL MODELS