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FLASH GENE

Symbol

GPR180

contributors: np - updated : 13-12-2005

HGNC name	G protein-coupled receptor 180
HGNC id	28899

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed GPR180 9 - 3922 49 440 - -

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular vessel       highly Reproductive female system uterus cervix   highly Respiratory respiratory tract larynx     moderately

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective bone

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a motif common to the Rhodopsin-like GPCR (G-protein-coupled receptor) superfamily

conjugated

GlycoP

HOMOLOGY

interspecies	ortholog to chimpanzee LOC467300
	ortholog to rattus MGC94555

Homologene

FAMILY

G protein-coupled receptor superfamily

CATEGORY

regulatory , receptor

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

might playing an important role in the regulation of vascular remodeling

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

induced by

up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene	a good target for development of drugs in the prevention of vascular restenosis
Marker
Therapy target

ANIMAL & CELL MODELS