Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol NARF contributors: mct - updated : 21-05-2008
HGNC name nuclear prelamin A recognition factor
HGNC id 29916
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY transport
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nuclear envelope,lamina
text
  • colocalized with LMNA at the nuclear lamina
    • basic FUNCTION
  • nemo-like kinase (NLK)-associated ring finger protein that regulates the ubiquitylation and degradation of T cell factor/lymphoid enhancer factor
  • involved in electron transport
  • having ferredoxin hydrogenase activity
  • involved in heterochromatin organization
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS electron transport
    PATHWAY
    metabolism
    signaling
    a component
  • component of a prelamin A endoprotease complex
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
  • specifically binding to the farnesylated prelamin A C-terminal domain (preAct)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS