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FLASH GENE
Symbol CATSPER3 contributors: - updated : 21-09-2007
HGNC name cation channel, sperm associated 3
HGNC id 20819
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • coiled-coil protein-protein interaction domains in the C-terminal tail
  • a single-ion transport domain with six transmembrane spanning regions, in which the fourth transmembrane region resembles a voltage sensor and a pore-forming region lies between transmembrane regions 5 and 6
    • mono polymer heteromer , tetramer
    HOMOLOGY
    intraspecies homolog to CATSPER1, CATSPER2
    Homologene
    FAMILY Catsper family
    CATEGORY receptor membrane ligand ion channel
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
    basic FUNCTION
  • voltage-gated Ca2+ channel
  • forms a functional heterotetrameric channel in sperm (in association with Casper 1, 2 and 3)
  • cation-channel protein having roles in acrosome reaction and male fertility
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    Ca2+ binding
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS