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FLASH GENE
Symbol MTMR12 contributors: - updated : 03-05-2006
HGNC name myotubularin related protein 12
HGNC id 18191
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a gram domain
  • a myotubularin-related domain
  • a tyrosine-protein phosphatase domain
    • HOMOLOGY
    interspecies homolog to murine Pip3ap
    Homologene
    FAMILY protein-tyrosine phosphatase family, non-receptor class myotubularin subfamily
    CATEGORY adaptor , receptor membrane tyrosine phosphatase
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    basic FUNCTION
  • lipid 3-phosphatase activity
  • function as an adaptator subunit in a complex with an active PtdIns(3)P 3-phosphatase
  • dual-specificity phosphatase acting on both phosphotyrosine and phosphoserine
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS