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FLASH GENE
Symbol DNAI1 contributors: mct - updated : 09-05-2007
HGNC name dynein, axonemal, intermediate chain 1
HGNC id 2954
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
five WD repeats
HOMOLOGY
interspecies ortholog to murine Dnaic1
ortholog to chimpanzee dnai1
Homologene
FAMILY dynein intermediate chain family
CATEGORY motor/contractile
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytoskeleton,microtubule
text
  • cilia in respiratory tract
  • flagella of spermatozoa
    • basic FUNCTION
  • dynein intermediate chain, outer arm, may be participating in regulating dynein activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense , reproduction/sex
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein tubulin
    cell & other microtubules
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ICS2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS