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FLASH GENE

Symbol

DNAI1

contributors: mct - updated : 09-05-2007

HGNC name	dynein, axonemal, intermediate chain 1
HGNC id	2954

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system testis     predominantly Respiratory respiratory tract trachea

cells

System Cell Pubmed Species Stage Rna symbol Reproductive germ cell Respiratory epithelial cell

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

five WD repeats

HOMOLOGY

interspecies	ortholog to murine Dnaic1
	ortholog to chimpanzee dnai1

Homologene

FAMILY

dynein intermediate chain family

CATEGORY

motor/contractile

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,cytoskeleton,microtubule
text	cilia in respiratory tract
	flagella of spermatozoa

basic FUNCTION

dynein intermediate chain, outer arm, may be participating in regulating dynein activity

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

immunity/defense , reproduction/sex

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

tubulin

cell & other

microtubules

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

ICS2

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS