Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

Home Page

FLASH GENE

Symbol

AMPD3

contributors: - updated : 05-01-2006

HGNC name	adenosine monophosphate deaminase (isoform E)
HGNC id	470

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

mono polymer

homomer , tetramer

HOMOLOGY

interspecies	ortholog to murine Ampd3
	homolog to Drosophila CG11058
	homolog to C.elegans C34F11.3

Homologene

FAMILY

adenosine and AMP deaminase family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm

basic FUNCTION	catalyzing the D amination of adenosin monophosphate into inosin monophosphate
	AMP deaminase plays a critical role in energy metabolism

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

nucleic

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

cytoplasmic membrane and phosphatidylinositol 4,5-bisphosphate

REGULATION

inhibited by	phosphatidylinositol 4,5-bisphosphate
	pH and association with plasmic membrane

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS