basic FUNCTION
| playing a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine |
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playing a key role in cholesterol metabolism |
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plays a critical role in the enterohepatic circulation of bile acids, as well as in cholesterol homeostasis |
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SLC10A1 and SLC10A2 are the best characterized family members, playing pivotal roles in hepatic and intestinal bile acid uptake respectively |
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is essential for maintaining the enterohepatic circulation of bile salts |
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is involved in both the recycling of bile acids and cholesterol homeostasis |
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has a crucial role in intestinal bile acid absorption |
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plays a central role in cholesterol homeostasis via the efficient reabsorption of bile acids from the distal ileum |