| basic FUNCTION
| being essential for the recognition and response to the disaccharide trehalose |
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having a role in glucose-mediated incretin release and may serve as the previously unknown gut lumen glucose sensor |
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required for the enhanced expression of SLC5A1 shown by enterocytes in response to luminal sugars or sweeteners |
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with TAS1R2, in addition to their role in taste perception, may also have a role in intrahepatic cholangiocytes (Toyono 2007) |
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with TAS1R1, believed to function in combination as a heteromeric glutamate taste receptor in humans (Chen 2009) |
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with TAS1R1, likely contributes to human umami taste perception (Chen 2009) |
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TAS1R2/TAS1R3 are involved in glucose-dependent secretion of satiation peptides  |
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with TAS1R2, mediating sweet taste perception (Fushan 2009) |
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TAS1R1/TAS1R3 are a direct sensor of the fed state and amino acid availability |
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TAS1R1 receptor subunit acts as an umami taste receptor in combination with its partner, TAS1R3 |
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effects of artificial sweeteners on adipose tissue biology may be largely independent of the classical sweet taste receptors, TAS1R2 and TAS1R3 |
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functions as a cell-surface glucose-sensing receptor in pancreatic beta-cells |
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TAS1R2 and TAS1R3 are likely to have a novel membrane trafficking system |
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TAS1R2/TAS1R3 are expressed in taste bud cells in the oral cavity and involved in membrane glucose sensing in endocrine cells regulating glucose homeostasis |
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TAS1R3 receptor protein plays an important role in control of glucose homeostasis not only by regulating sugar intake but also via its extraoral function, probably in the pancreas and brain |
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TAS1R3 and its associated heterotrimeric GNAT3 are involved |
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in sweet and umami sensing in taste cells |
