Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol UGT1A9 contributors: mct/npt - updated : 24-04-2009
HGNC name UDP glycosyltransferase 1 family, polypeptide A9
HGNC id 12541
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated GlycoP
HOMOLOGY
interspecies ortholog to rattus Ugt1a8
intraspecies homolog to UGT1A10 (93 p100)
Homologene
FAMILY
  • UDP-glycosyltransferase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • transfer of glucuronic acid (or other nucleotide sugars) to bilirubin
  • catalyze the transfer of glucuronic acid from UDP-glucuronic acid to endo- and xenobiotics in our body (Patana 2008)
  • having a major role in the elimination of lipophilic chemicals by glucuronidation
  • catalyze the glucuronidation of xenobiotics, mutagens, and reactive metabolites and thus act as indirect antioxidants (Kalthoff 2010)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to colon cancer (Girard (2008)
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS