protein
| chondroitin sulfate, Ii-CS  |
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associated with CD4  |
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collagen type XIV alpha 1, COL14A1  |
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interacts with the ezrin-radixin-moesin family of cytoskeletal adaptors |
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T-lymphocyte specific protein tyrosine kinase p56lck  |
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membrane-binding partner for ezrin/radixin/moesin (ERM) proteins  |
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versican, VCAN  |
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metalloproteinase-9, MMP-9 |
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T-cell lymphoma invasion and metastasis 1, TIAM1  |
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vav 2 guanine nucleotide exchange factor, VAV2  |
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contributes to the endocytosis and metabolism of hyaluroran |
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dentin matrix protein 1, DMP1 and osteopontin, SPP1  |
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transforming growth factor, beta receptor 1, TGFBR1  |
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ezrin, EZR  |
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Protein 4.1 tumor suppressor, Protein 4.1R  |
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c-Src kinase  |
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Rac1-dependent protein kinase N-gamma, PKNgamma  |
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SMAD family member 1, SMAD1  |
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epidermal growth factor receptor, EGFR and v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), ERBB2  |
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matrix metallopeptidase 7 (matrilysin, uterine), MPP7  |
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RhoA-specific guanine nucleotide exchange factor, p115RhoGEF in human metastatic breast tumor cells (MDA-MB-231 cell line)  |
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ankyrin and inositol 1,4,5-triphosphate receptor, type 3, ITPR3  |
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glycosaminoglycan hyaluronan receptor |
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HMMR (HMMR and CD44 act together in a hyaluronan-dependent autocrine mechanism to coordinate sustained signaling through ERK1,2, leading to high basal motility of invasive breast cancer cells)  |
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cytoskeletal linker protein ezrin (modulated by phosphorylation of Ser291 and this phosphorylation is critical for CD44-dependent directional cell motility)  |
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receptor-ligand relationships between CD44 and LGALS8, interactions which may affect the extent of the autoimmune inflammatory response in the synovial fluid of rheumatoid arthritis patients  |
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hyaluronan (hyaluronan induces cell death in activated T cells through CD44)  |
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physical association between CD44 and ITGA4 |
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CD44 is the first identified endogenous ligand of CLEC4G, and similarly, that CLEC4G is a novel ligand of CD44  |
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interacting with SELL (TM domains of SELL and CD44 play a crucial role in cell adhesion under flow by targeting receptors to microvilli or the cell body, respectively)  |
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interacts with importin family members and this transportin-dependent pathway is the mechanism whereby full-length CD44 enters the nucleus  |
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functional interaction with transportin requires the membrane-proximal 20 AAs of the cytoplasmic tail of CD44 that contain the TNPO1-specific NLS  |
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interacting with MMP9 (initiates cross-talk between CD44 and EGFR, which in turn activates downstream effectors for cell migration)  |
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major hyaluronan (HA) receptor, taht is a novel partner for podoplanin (PDPN)  |
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role of MARCH8 and MARCH4 in the regulated turnover of CD81 and CD44, two ubiquitously expressed, multifunctional proteins  |
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in the presence of an hyaluronan-rich matrix, HA (hyaluronan) binds to CD44 and alters a fibroblast proliferative response to TGFB1, whereas in a non-HA-rich environment, TGFB1 mediates its responses through other CD44-independent pathways, such as the Smad pathway  |
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MARCH8 expression completely shifted the trafficking of CD44 and CD98 proteins away from recycling tubules to early endosome antigen 1 compartments and late endosomes, resulting in reduced surface levels  |
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LRP1-mediated internalization of CD44 appeared critical to define the adhesive properties of tumor cells  |
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MME might be involved in the development of endometriosis due to its influence on CD44-dependent cell adhesion  |
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CD44 of control chondrocytes was found to interact and co-immunoprecipitate with both the 65- and 130-kDa isoforms of ANK3  |
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SND1 promotes the inclusion of CD44 variable exons by recruiting KHDRBS1 and spliceosomal components on CD44 pre-mRNA  |
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CD44 is a key downstream target of HNRNPM  |
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PRG4 (lubricin) is a novel putative ligand for CD44 and may control synoviocyte overgrowth in inflammatory arthropathies via a CD44-mediated mechanism  |
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interaction of TM4SF5 with CD44 promotes self-renewal and circulating capacities of hepatocarcinoma cells  |
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PRG4 may play a role in modulating inflammatory responses through interaction with CD44  |
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important role for IMPG1 and CD44 in the development of photoreceptors and IPM (interphotoreceptor matrix) formation during human retinogenesis  |