basic FUNCTION
| involved in developmental regulation |
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acting as a key regulator in the development of cell-mediated immunity |
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involved in late neuronal development |
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may helps effect a cellular response to a morphogen gradient |
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important role for TFAP2C, SMARCA4, and EOMES in trophoblast stem cell self-renewal |
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with CDX2, are regarded as the key transcription factors required for the establishment of a functional trophectoderm |
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essential for epithelial-to-mesenchymal transition, mesoderm migration and specification of definitive endoderm during gastrulation |
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controls interleukin-5 production in memory T helper 2 cells through inhibition of activity of the transcription factor GATA3 |
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transcription factors CDX2 and EOMES may play critical roles in induced trophoblast progenitor (iTP) cell generation |
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TBX2, TBX3, TBX4, TBX5 and three members of TBX1 (TBX1, TBX15, TBX18), Brachyury (T) and Eomes (TBR2) are expressed in the developing limb |