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FLASH GENE
Symbol KCNG1 contributors: - updated : 02-06-2007
HGNC name potassium voltage-gated channel, subfamily G, member 1
HGNC id 6248
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivemale systemprostate   
 male systemtestis   
Skin/Tegumentskin    
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectivebone   
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text placenta
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six putative membrane-spanning domains and an hydrophobic pore including the P domain with the K+ channel signature
  • TM domains 5 and 6, sensitive to changes in membrane potential
  • mono polymer heteromer , tetramer
    HOMOLOGY
    interspecies homolog to rattus Ik8
    Homologene
    FAMILY potassium channel, voltage-gated, subfamily G
    CATEGORY transport channel
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • may need to associate with another protein to form a
  • functional channel
  • may modulate channel activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS