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FLASH GENE
Symbol MICALCL contributors: mct/npt - updated : 29/11/2008
HGNC name MICAL C-terminal like
HGNC id 25933
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrinethyroid    
Reproductivemale systemtestis  highly Homo sapiens
Respiratoryrespiratory tractlarynx   
Visualeye    
cells
SystemCellPubmedSpeciesStageRna symbol
Reproductivespermatid Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • MAPK1-binding domain required for phosphorylation of MICALCL
  • conjugated PhosphoP
    HOMOLOGY
    Homologene
    FAMILY
  • MICAL family
  • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION extracellular
        intracellular
    intracellular,cytoplasm,cytosolic
    basic FUNCTION
  • having a function in plexin-mediated axonal repulsion
  • interactor of MAPK1 in the intracellular signal transduction pathway that occurs during the morphogenetic
  • downstream interactor of MAPK1 that participates in the intracellular signal transduction pathway mediating the morphogenetic development of round spermatids into spermatozoa development of round spermatids to spermatozoa
  • downstream interactor of MAPK1 that participates in the intracellular signal transduction pathway mediating the morphogenetic development of round spermatids into spermatozoa
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • bound to nonphosphorylated and phosphorylated forms of MAPK3 and MAPK1 (MAPK1-binding domain was required for phosphorylation of EBITEIN1)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS