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FLASH GENE
Symbol FAM83B contributors: mct - updated : 07-12-2001
HGNC name family with sequence similarity 83, member B
HGNC id 21357
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY FAM83 family
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION
basic FUNCTION unknown
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
  • PLD1 interacting with FAM83B (elevated FAM83B expression and suppression of PLD1 activity prevents FAM83B-mediated transformation)
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerreproductivebreast
    ablation of FAM83B expression from breast cancer cells inhibited EGFR phosphorylation and suppressed cell proliferation
    ANIMAL & CELL MODELS