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FLASH GENE
Symbol FAM83B contributors: mct - updated : 07-12-2001
HGNC name family with sequence similarity 83, member B
HGNC id 21357
Location 6p12.1      Physical location : 54.711.568 - 54.806.817
Synonym name
  • chromosome 6 open reading frame 143
  • hypothetical protein LOC222584
    • Synonym symbol(s) FLJ30642, C6orf143, MGC126677, MGC138480
    DNA
    TYPE functioning gene
    STRUCTURE 95.00 kb     5 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 3167 115 1011 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY FAM83 family
    CATEGORY unknown/unspecified
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • PLD1 interacting with FAM83B (elevated FAM83B expression and suppression of PLD1 activity prevents FAM83B-mediated transformation)
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    cancerreproductivebreast
    ablation of FAM83B expression from breast cancer cells inhibited EGFR phosphorylation and suppressed cell proliferation
    ANIMAL & CELL MODELS