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FLASH GENE
Symbol UTP14A contributors: npt/mct - updated : 17-09-2019
HGNC name UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
HGNC id 10665
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
 intestinelarge intestine   
Lymphoid/Immunetonsils   predominantly
cell lineage
cell lines various cancer
fluid/secretion serum
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • UTP14 family
  • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     intracellular
    basic FUNCTION
  • playing a role in normal spermatogenic cell development
  • UTP14A is a direct interaction partner of DHX37 and can likely act as a cofactor that stimulates the activity of the helicase in the context of U3 snoRNA release
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • conserved sequence motif in UTP14A interacts with and activates DHX37 by stimulating its ATPase activity and enhancing RNA binding
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS