protein
| binding TIMPs in a 1:1 stoechiometry |
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interacting with RUNX2 (phosphorylation of RUNX2 sites necessary for PKA stimulated MMP13 promoter activation and this event may be critical for bone remodeling) ![](pubmed.jpg) |
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HDAC4 is a basal repressor of MMP13 transcription, and PTH regulates HDAC4 to control MMP13 promoter activity ![](pubmed.jpg) |
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IL6 increased the migration and expression of MMP13 in chondrosarcoma cells ![](pubmed.jpg) |
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NOV increased the migration and expression of matrix metalloproteinase MMP13 in chondrosarcoma cells ![](pubmed.jpg) |
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CEBPB and RUNX2 cooperatively enhanced promoter activity of MMP13 through specific binding to a CEBP-binding motif and an osteoblast-specific cis-acting element 2 motif as a protein complex ![](pubmed.jpg) |
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WNT5A-ROR2 signaling might be required for expression of MMP13 gene during the development of the cartilaginous tissue ![](pubmed.jpg) |
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novel role for ELF3 as a procatabolic factor that may contribute to cartilage remodeling and degradation by regulating MMP13 gene transcription ![](pubmed.jpg) |
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possible involvement of S100A12 in the development of osteoarthritis (OA) by up-regulating MMP13 and VEGFA via MAPK14 and NFKB1 pathways ![](pubmed.jpg) |
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MMP13 is an important target of Osterix (SP7) ![](pubmed.jpg) |
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physical and functional interaction between SP7 and RUNX2 were necessary for the induction of MMP13 during endochondral ossification ![](pubmed.jpg) |
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direct regulatory role for SP7 in MMP13 gene expression in osteoblasts ![](pubmed.jpg) |
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promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP13 ![](pubmed.jpg) |
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IL6 mediates suppression of ACAN and induction of MMP13 expression by NOTCH1 in chondrocytes ![](pubmed.jpg) |
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inhibition of MMP13 expression through GDF5 stimulation is mediated by DKK1 ![](pubmed.jpg) |
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MMP13 proteolyzes FBLN1 and CALU protects FBLN1 from cleavage by MMP13 ![](pubmed.jpg) |
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IL32 stimulation promotes the invasion and motility of osteosarcoma cells, possibly via the activation of AKT1 and the upregulation of MMP13 expression ![](pubmed.jpg) |
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