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FLASH GENE

Symbol

KIR2DS4

contributors: np/ - updated : 10-04-2006

HGNC name	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
HGNC id	6336

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

text	alternatively spliced (truncated) forms (PMID: 8662091)

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_012314 8 - 1586 NP_036446 - 304 - 1996 8662091

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Lymphoid

cells

System Cell Pubmed Species Stage Rna symbol Lymphoid/Immune lymphocyte

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	two Ig extracellular domains
	a short cytoplasmic tail

HOMOLOGY

Homologene

FAMILY	immunoglobulin superfamily
	natural killer cell receptors family

CATEGORY

immunity/defense , receptor membrane

SUBCELLULAR LOCALIZATION	plasma membrane
text	type 1 membrane protein

basic FUNCTION

playing a role in recognizing major histocompatibility class I molecules on target cells

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

immunity/defense

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS