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FLASH GENE
Symbol CSDE1 contributors: mct/npt - updated : 24-04-2009
HGNC name cold shock domain containing E1, RNA-binding
HGNC id 29905
RNA
TRANSCRIPTS type messenger
text multiple transcripts produced by multiple polyadenylation sites and alternative splicing (Jeffers)
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
20 - 4115 88.7 798 - Jeffers (1990)
- - 4216 90.5 813 - Jeffers (1990)
19 - 4041 85.6 767 - Jeffers (1990)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Lymphoid/Immunelymph node   highly
Reproductivemale systemtestis  highly
Skin/Tegumentskin   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to rattus unr
homolog to murine D3Jfr1
homolog to Drosophila CG7015
homolog to Xenopus Xl.4677
Homologene
FAMILY
  • cold-shock domain (CSD) family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • required for internal initiation of translation of rhinovirus RNA
  • involved in translational regulation of specific genes
  • playing a role with HNRPC in internal initiation of translation during mitosis
  • internal initiation trans-acting factor (ITAF) in the cap-independent translation of some particular viral and cellular mRNAs (Cornelis 2005)
  • RNA-binding protein involved in the regulation of messenger RNA stability and internal initiation of translation (Dormoy-Raclet 2007)
  • acting as a positive or negative regulator of cell death, depending on the cell type (Dormoy-Raclet 2007)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    text male gonad development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding to UNRIP
    • cell & other
    REGULATION
    Other developmentally regulated expression in the testis
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS