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FLASH GENE
Symbol DUSP22 contributors: - updated : 18-03-2006
HGNC name dual specificity phosphatase 22
HGNC id 16077
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Cardiovascularheart    
Endocrinepancreas    
Reproductivemale systemtestis   
Respiratorylung    
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Connective    
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
one single DSP catalytic domain
HOMOLOGY
interspecies homolog to murine Lmw-dsp2
intraspecies homolog to DUSP15
Homologene
FAMILY mitogen-activated protein kinase phosphatase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
intracellular,nucleus
basic FUNCTION may be dephosphorylating and inactivating MAP kinases
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein binding to P38 and SAPK (dephosphorylation and deactivaction)
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS