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FLASH GENE
Symbol DUSP22 contributors: - updated : 18-03-2006
HGNC name dual specificity phosphatase 22
HGNC id 16077
DNA
TYPE functioning gene
STRUCTURE 59.00 kb     8 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC389451 6 LOC389451 HLA-DRB9 6p21.3 major histocompatibility complex, class II, DR beta 9 (pseudogene) LOC391863 6 similar to Olfactory receptor 4F3 HLA-DRB5 6p21.3 major histocompatibility complex, class II, DR beta 5 LOC389356 6 similar to bA476I15.3 (novel protein similar to septin) HLA-DRB6 6p21.3 major histocompatibility complex, class II, DR beta 6 (pseudogene) HLA-DRB1 6p21.3 major histocompatibility complex, class II, DR beta 1 C6orf35 6q25.3 chromosome 6 open reading frame 35 LOC389357 6 LOC389357 DUSP22 6p24.3 dual specificity phosphatase 22 IRF4 6p25-p23 interferon regulatory factor 4 SEC5 LOC391990 6 similar to serine palmitoyltransferase, long chain base subunit 2; serine palmitoyltransferase, subunit II HUS1B 6p25.3 HUS1 checkpoint homolog b (S. pombe) LOC340177 6q27 hypothetical LOC340177 LOC389452 6 LOC389452 LOC391991 6 similar to lysR-like transcriptional regulator LOC391992 6 similar to putative heavy metal transporter LOC391993 6 similar to F22G5.20 LOC391994 6 similar to Hypothetical protein FLJ30525 LOC221768 6p25.3 similar to ENSANGP00000010305 FOXQ1 6p25-p23 forkhead box Q1 LOC389358 6 LOC389358 FOXF2 6p25.3 forkhead box F2 LOC221766 6p25.3 hypothetical LOC221766 LOC389359 6 LOC389359 LOC389360 6 LOC389360 LOC389361 6 LOC389361 FOXC1 6p25 forkhead box C1 GMDS 6p25 GDP-mannose 4,6-dehydratase
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
Cardiovascularheart    
Endocrinepancreas    
Reproductivemale systemtestis   
Respiratorylung    
Visualeye    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoieticbone marrow   
Connective    
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
one single DSP catalytic domain
HOMOLOGY
interspecies homolog to murine Lmw-dsp2
intraspecies homolog to DUSP15
Homologene
FAMILY mitogen-activated protein kinase phosphatase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,cytosolic
intracellular,nucleus
basic FUNCTION may be dephosphorylating and inactivating MAP kinases
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein binding to P38 and SAPK (dephosphorylation and deactivaction)
cell & other
REGULATION
ASSOCIATED DISORDERS
ANIMAL & CELL MODELS