Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | IMPA2 | contributors: mct - updated : 27-05-2014 |
HGNC name | inositol(myo)-1(or 4)-monophosphatase 2 |
HGNC id | 6051 |
|
DNA |
TYPE | like-sequence |
SPECIAL FEATURE | arranged in tandem |
STRUCTURE | 49.00 kb 8 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
regulatory sequence | Promoter |
Binding site transcription factor | |
text structure | multiple potential binding sites for Sp1 and consensus motifs for AP2 and other transcription factors |
MAPPING | cloned | Y | linked | status | confirmed |
Map | pter - D18S482 - IMPA2 - PTPN2 - D18S71 - cen |
Authors | Gene Map (98) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
physiological period | fetal, pregnancy |
Text | tissues, placenta |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
|
mono polymer | homomer , dimer |
HOMOLOGY |
intraspecies | homolog to IMPA1 |
Homologene |
FAMILY | inositol monophosphatase family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth |
basic FUNCTION | |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
phosphatidyl inositol signaling pathway |
a component |
INTERACTION |
DNA |
RNA |
small molecule | cofactor, |
Mg++ |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | FEB6 |
Susceptibility |
|
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |