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FLASH GENE
Symbol KLRG1 contributors: npt - updated : 09-12-2002
HGNC name killer cell lectin-like receptor subfamily G, member 1
HGNC id 6380
DNA
TYPE functioning gene
STRUCTURE 21.12 kb     5 Exon(s)    1 Copie(s)
10 Kb 5' upstream gene genomic sequence study
motif repetitive sequence   long interspersed repetitive elements
text structure line-1-like element and a (CTT
170 triplet repeat in intron sequence
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
5 - 1815 21.2 189 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticspleen    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / Hematopoietic    
Connective    
Lymphoid    
cells
SystemCellPubmedSpeciesStageRna symbol
 mast cell
Blood/Hematopoieticbasophil
Blood/HematopoieticNK cell
cell lineage
cell lines basophilic leukemia cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • extracytoplasmic carbohydrate recognition domain homolog
  • the C type lectin family member, group V, like Ly-49
  • a cytoplasmic tail containing an immunoreceptor tyrosine-based inhibition motif (ITIM)
  • four potential N-glycosylation sites
  • HOMOLOGY
    interspecies homolog to murine Klrg1
    Homologene
    FAMILY
  • natural killer cell lectin-like receptor
  • subfamily G, in the NK (natural killer) complex (NKG2@)
  • CATEGORY immunity/defense , receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    text type 2 membrane protein
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS