basic FUNCTION
| involved in the transport of early processed glycoprotein from endoplasmic reticulum to Golgi |
|
may facilitate glycoprotein transport with only low efficiency via its lectin function |
|
membrane-bound lectin protein that cycles between the ER and Golgi |
|
intracellular transport receptor of SERPINA1 |
|
LMAN1 and MCFD2 form a Ca(2+)-dependent cargo receptor that cycles between the endoplasmic reticulum (ER) and the ER-Golgi intermediate compartment for efficient transport of FV/FVIII from the ER to the Golgi |
|
glycoprotein receptor, mediating transfer from the ER to the ER-Golgi intermediate compartment |
|
with the co-receptor MCFD2, it transports coagulation factors V and VIII |
|
central role of LMAN1 in regulating the binding in the ER and the subsequent release in the ERGIC of FV and FVIII |
|
LMAN2, LMAN2L, LMAN1, participate in the vectorial transport of glycoproteins via sugar-protein interactions |
|
|