| basic FUNCTION
| major motor protein complex responsible for minus-end microtubule-based motile processes |
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dynein light chain involved in cargo binding and has a key role in multiple steps of hippocampal neuron development, including initial neurite sprouting, axon specification, and later dendritic elaboration  |
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play a role in G protein signaling activation and neuronal growth |
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a negative regulator of ARHGEF2 |
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required to determine the orientation of mitotic precursor cell divisions in vivo and its interaction with Arhgef2 is necessary to regulate cortical neurogenesis |
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important in embryonic neural precursors, a part of an essential pathway that regulates the genesis of neurons from cortical precursor cells, potentially by regulating mitotic spindle orientation |
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role of DYNLT1 in S-phase entry is dispensable in non-ciliated cells |
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DYNLT1 phosphorylated at Thr 94 is selectively enriched at the ciliary transition zones of cortical neural progenitors, and has a key role in controlling G(1) length, cell cycle entry and fate determination of these cells during corticogenesis |
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has critical functions as an adapter between the dynein motor complexes and cytoplasmic vesicles, suggesting the involvement of the DKK3 protein in the ER-related vesicular trafficking system |
