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FLASH GENE
Symbol ST8SIA6 contributors: mlc - updated : 27-10-2007
HGNC name ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
HGNC id 23317
DNA
TYPE functioning gene
STRUCTURE 134.00 kb     8 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
8 - 1398 - 398 - Avril (2006)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveintestinesmall intestine   
Reproductivefemale systembreastmammary gland  
 female systemovary   
 male systemtestis   
Skin/Tegumentskin    
Urinarybladder    
 kidney   predominantly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conserved motifs of sialyltransferases
HOMOLOGY
Homologene
FAMILY glycosyltransferase 29 family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,Golgi
basic FUNCTION
  • prefers O-glycans to N-glycans or glycolipids as acceptor substrates
  • exhibited activity toward oligosaccharides such as sialyllactose and sialyllactosamine
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism protein
    signaling
    protein glycosylation
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS