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FLASH GENE
Symbol DDX50 contributors: npt/ - updated : 12-05-2006
HGNC name DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
HGNC id 17906
DNA
TYPE functioning gene
SPECIAL FEATURE arranged in tandem
text arranged in tandem with DDX21
STRUCTURE 45.57 kb     15 Exon(s)
10 Kb 5' upstream gene genomic sequence study
text structure no TATA box
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text several trancripts resulting from exon inclusion or exon skipping
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
15 - 2575 82.4 737 - Valdez (2002)
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • N terminal DEAD/H box (Asp-Glu-Ala-Asp/His)
  • dsRNA helicase domain
  • a ssRNA foldase C terminal domain
  • HOMOLOGY
    Homologene
    FAMILY
  • DEAD box helicase family
  • DDX21/DDX50 subfamily
  • CATEGORY enzyme , RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleolus
    basic FUNCTION
  • unwinding double stranded RNA and folding single stranded RNA
  • CELLULAR PROCESS protein, editing
    cell organization/biogenesis
    PHYSIOLOGICAL PROCESS
    text ribosomal RNA biogenesis
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
  • ATP
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS