basic FUNCTION
| may function as an antiproliferative and antitumor agent |
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playing a pivotal role in the regulation of cytokine production induced by pathogens |
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implicated in innate immunity by sensing intracellular viral RNAs and inducing type I IFN production |
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critical regulatory role in modulating the generation and differentiation of granulocytes |
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initiates a signaling cascade that activates innate immune response by interferon and cytokine production, providing essential antiviral protection for the host |
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cytosolic receptor that recognizes viral RNA and activates the interferon-mediated innate antiviral response |
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playing a critical regulatory role in modulating the generation and differentiation of granulocytes (negatively regulating granulocytic proliferation) |
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with HRASLS2 and PLA2G16, are involved in the phospholipid metabolism with different physiological roles |
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important viral RNA recognition molecule, associated with the actin cytoskeleton and localized predominantly to actin-enriched membrane ruffles in non-polarized epithelial cells |
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physiological role in the regulation of cellular migration |