Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | DLG2 | contributors: mct - updated : 10-03-2022 |
HGNC name | discs, large homolog 2, chapsyn-110 (Drosophila) |
HGNC id | 2901 |
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Location | 11q14.1 Physical location : 83.166.055 - 85.338.314 |
Synonym name | |
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Synonym symbol(s) | PSD-93, chapsyn-110, PPP1R58, PSD93, FLJ37266, MGC131811, DKFZp781D1854, DKFZp781E0954 |
DNA |
TYPE | functioning gene |
STRUCTURE | 2172.26 kb 23 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | provisional |
Map | cen - D11S901 - D11S4568 - D11S4572 - D11S1365 - D11S4409 - DLG2 /D11S4391 - D11S4634 - D11S4576 - D11S4187 - D11S4135 - qter |
Authors | Stathakis (98) |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type |
expressed in | (based on citations) |
organ(s) |
tissue |
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cells |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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mono polymer | heteromer , dimer |
HOMOLOGY |
interspecies | homolog to Drosophila tumor suppressor gene,discs large (Dlg) |
homolog to rattus Chapsyn-110 | |
homolog to C.elegans c25f6.2 |
intraspecies | homolog to sap97 and psd95 |
Homologene |
FAMILY | MAGUK (membrane-associated guanylate kinase homolog) family of cell junction proteins |
CATEGORY | enzyme , signaling |
SUBCELLULAR LOCALIZATION | plasma membrane,junction |
intracellular | |
intracellular,cytoplasm,cytosolic | |
text | postsynaptic sites |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
text | small molecule transport |
PATHWAY |
metabolism |
signaling | neurotransmission , signal transduction |
a component | heterodimerizing with DLG4 and recruited into the same NMDA receptor and Shaker-type potassium channel clusters |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
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Variant & Polymorphism other | |
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |