protein
| binding to IgE |
|
MS4A2 acts as a critical element in mast cell synergistic degranulation response through FCER1A |
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PTPRE negatively regulates FCER1A-mediated signalling pathways and thus constitutes a novel target for ameliorating allergic conditions |
|
like INPP5D, UBASH3B functions as a negative regulator of FCER1A signaling in mast cells |
|
SPI1 and GATA1 transactivate FCER1A |
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DOCK5 functions as a key signaling adaptor that links FCER1A signals to microtubule dynamics during mast cell degranulation |
|
SH3BP2 is a cytoplasmic adaptor protein that acts as a positive regulator in mast cell FCER1A-dependent signaling |
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functional interaction between FCER1A and ANPEP on mast cell (MC) |
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PLSCR1 aggravates anaphylactic reactions by increasing FCER1A-dependent mast cell degranulation |