Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | NAA10 | contributors: mct - updated : 28-04-2017 |
HGNC name | N(alpha)-acetyltransferase 10, NatA catalytic subunit |
HGNC id | 18704 |
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Corresponding disease |
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Location | Xq28 Physical location : 153.195.376 - 153.200.468 | ||||
Synonym name | |||||
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Synonym symbol(s) | TE2, DXS707, NACTH, ARD1, ARD1A, ARD1P, OGDNS, DXS707, MCOPS1, hARD1 | ||||
EC.number | 2.3.1.88/ 2.3.1.255 |
DNA |
TYPE | functioning gene |
STRUCTURE | 5.33 kb 8 Exon(s) |
MAPPING | cloned | Y | linked | N | status | provisional |
Map | see L1CAM |
regionally located | located 5' to L1CAM |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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HOMOLOGY |
interspecies | homolog to yeast S.cerevisiae ard1 N-acetyltransferase |
homolog to murine Ard1 | |
homolog to Drosophila CG11989 | |
homolog to C.elegans K07H8.3 |
Homologene |
FAMILY | |
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CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,organelle,mitochondria | |
intracellular,nucleus | |
text | |
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basic FUNCTION | |
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CELLULAR PROCESS | nucleotide, chromatin organization, remodeling |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | complexing with NARG1, displaying alpha (N-terminal) acetyltransferase activity |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
Phosphorylated by | IKBKB (IKBKB physically associated with NAA10 and phosphorylated it at Ser209) |
Other | cleaved by caspases during apoptosis |
negative regulation of NAA10 towards NTN1 and its receptor UNC5B were also detected upon treatment of all-trans retinoid acid, which was often used to induce morphological differentiation |
ASSOCIATED DISORDERS |
corresponding disease(s) | NATD , MCOPS1 |
Susceptibility |
Variant & Polymorphism |
Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |